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Nucleus Accumbens Core. The nucleus accumbens NAc is clearly implicated in reward processing and drug addiction as well as in numerous neurological and psychiatric disorders. The nucleus accumbens receives glutaminergic dopaminergic and histaminergic input fibers from different areas of the brain. Its former name nucleus accumbens septi a nucleus leaning against the septum refers to a medial hook-shaped expansion of this anteroventral region of the striatum which curves under the floor of the frontal horn of the lateral ventricle and ascends for. The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle.

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It is also called nucleus accumbens core or NAcc core. In general this result has held up in subsequent studies using different variants of the delayed discounting procedure. The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens. NAshell nucleus accumbens shell. The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior.

Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards.

The nucleus accumbens NAc is clearly implicated in reward processing and drug addiction as well as in numerous neurological and psychiatric disorders. It is present in the inner region of the nucleus accumbens. The nucleus accumbens receives glutaminergic dopaminergic and histaminergic input fibers from different areas of the brain. In two experiments we induced nucleus accumbens core NAcc dysfunction in rats receiving fear discrimination consisting of cues for danger uncertainty and safety. The medium spiny neurons in the nucleus accumbens receive input from both the dopaminergic neurons of the VTA and the glutamatergic neurons of the hippocampus amygdala and medial prefrontal cortex. Functional differentiation in valence processing has previously been found along the rostrocaudal axis of the shell region of the NAc in assessments of unconditioned motivation.

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Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards. NAcore nucleus accumbens core. In general this result has held up in subsequent studies using different variants of the delayed discounting procedure. Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards. Rapid discrimination of uncertain threat and safety.

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Nevertheless the circuit mechanisms underlying the diverse functions of the NAc remain poorly understood. Consistent with our previous findings 34 35 FGF2 mRNA levels in the core of the nucleus accumbens were higher in bHRs relative to bLRs under basal conditions t 9 577 P 00003 and these differences were also apparent following prolonged cocaine self-administration t 9 242 P 0038 Fig. 48 initially reported that selective bilateral excitotoxic lesions of the nucleus accumbens core region but not the anterior cingulate or the medial PFC resulted in more impulsive choice using a temporal discounting task. Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards. The nucleus accumbens NAc is thought to be a site of integration of positively and negatively valenced information and action selection.

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NMDA N-methyl- D -aspartic acid. Consistent with our previous findings 34 35 FGF2 mRNA levels in the core of the nucleus accumbens were higher in bHRs relative to bLRs under basal conditions t 9 577 P 00003 and these differences were also apparent following prolonged cocaine self-administration t 9 242 P 0038 Fig. NAshell nucleus accumbens shell. Functional differentiation in valence processing has previously been found along the rostrocaudal axis of the shell region of the NAc in assessments of unconditioned motivation. The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens.

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Evidence suggests that core and shell subregions may play dissociable roles in guiding motivated behavior. The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens. NMDAR N-methyl- D -. Permanent NAcc dysfunction via neurotoxic lesion generally disrupted the ability to scale fear to degree of threat and specifically impaired one component of scaling. Previous studies suggest that.

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NAshell nucleus accumbens shell. The medium spiny neurons in the nucleus accumbens receive input from both the dopaminergic neurons of the VTA and the glutamatergic neurons of the hippocampus amygdala and medial prefrontal cortex. To directly reveal NAcc threat responding we recorded single-unit activity from 7 female rats undergoing Pavlovian fear discrimination. In two experiments we induced nucleus accumbens core NAcc dysfunction in rats receiving fear discrimination consisting of cues for danger uncertainty and safety. Its former name nucleus accumbens septi a nucleus leaning against the septum refers to a medial hook-shaped expansion of this anteroventral region of the striatum which curves under the floor of the frontal horn of the lateral ventricle and ascends for.

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The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle. Rapid discrimination of uncertain threat and safety. More recently our laboratory has shown the NAcc is necessary to discriminate cues for threat and safety. Evidence suggests that core and shell subregions may play dissociable roles in guiding motivated behavior. Consistent with our previous findings 34 35 FGF2 mRNA levels in the core of the nucleus accumbens were higher in bHRs relative to bLRs under basal conditions t 9 577 P 00003 and these differences were also apparent following prolonged cocaine self-administration t 9 242 P 0038 Fig.

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The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens. The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle. Consistent with our previous findings 34 35 FGF2 mRNA levels in the core of the nucleus accumbens were higher in bHRs relative to bLRs under basal conditions t 9 577 P 00003 and these differences were also apparent following prolonged cocaine self-administration t 9 242 P 0038 Fig. The NAc is necessary for using information about expected outcome values to guide behavior after reinforcer devaluation. NMDA N-methyl- D -aspartic acid.

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The NAc is necessary for using information about expected outcome values to guide behavior after reinforcer devaluation. The nucleus accumbens NAc is thought to be a site of integration of positively and negatively valenced information and action selection. It is present in the inner region of the nucleus accumbens. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior. Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards.

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Evidence suggests that core and shell subregions may play dissociable roles in guiding motivated behavior. In two experiments we induced nucleus accumbens core NAcc dysfunction in rats receiving fear discrimination consisting of cues for danger uncertainty and safety. The nucleus accumbens NAc is clearly implicated in reward processing and drug addiction as well as in numerous neurological and psychiatric disorders. NAcore nucleus accumbens core. NMDAR N-methyl- D -.

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Previous studies suggest that. NMDAR N-methyl- D -. Nevertheless the circuit mechanisms underlying the diverse functions of the NAc remain poorly understood. Evidence suggests that core and shell subregions may play dissociable roles in guiding motivated behavior. 48 initially reported that selective bilateral excitotoxic lesions of the nucleus accumbens core region but not the anterior cingulate or the medial PFC resulted in more impulsive choice using a temporal discounting task.

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NMDA N-methyl- D -aspartic acid. NMDAR N-methyl- D -. The nucleus accumbens receives glutaminergic dopaminergic and histaminergic input fibers from different areas of the brain. To directly reveal NAcc threat responding we recorded single-unit activity from 7 female rats undergoing Pavlovian fear discrimination. The nucleus accumbens core AcbC is a primary candidate as zif268 is up-regulated in the AcbC as well as in the BLA following exposure to cocaine CSs Thomas et al.

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The nucleus accumbens NAc is thought to be a site of integration of positively and negatively valenced information and action selection. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior. The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens. It is considered to be the part of ventral striatum of the basal ganglia. The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle.

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The nucleus accumbens core is with the nucleus accumbens shell a subregion of the nucleus accumbens. The medium spiny neurons in the nucleus accumbens receive input from both the dopaminergic neurons of the VTA and the glutamatergic neurons of the hippocampus amygdala and medial prefrontal cortex. In general this result has held up in subsequent studies using different variants of the delayed discounting procedure. Its former name nucleus accumbens septi a nucleus leaning against the septum refers to a medial hook-shaped expansion of this anteroventral region of the striatum which curves under the floor of the frontal horn of the lateral ventricle and ascends for. It is present in the inner region of the nucleus accumbens.

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The region of fusion between the head of the caudate nucleus and the putamen covered on its inferior aspect by the olfactory tubercle. Functional differentiation in valence processing has previously been found along the rostrocaudal axis of the shell region of the NAc in assessments of unconditioned motivation. Consistent with our previous findings 34 35 FGF2 mRNA levels in the core of the nucleus accumbens were higher in bHRs relative to bLRs under basal conditions t 9 577 P 00003 and these differences were also apparent following prolonged cocaine self-administration t 9 242 P 0038 Fig. Rapid discrimination of uncertain threat and safety. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior.

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Permanent NAcc dysfunction via neurotoxic lesion generally disrupted the ability to scale fear to degree of threat and specifically impaired one component of scaling. The NAc is necessary for using information about expected outcome values to guide behavior after reinforcer devaluation. The medium spiny neurons in the nucleus accumbens receive input from both the dopaminergic neurons of the VTA and the glutamatergic neurons of the hippocampus amygdala and medial prefrontal cortex. The NAc is necessary for using information about expected outcome values to guide behavior after reinforcer devaluation. The nucleus accumbens NAc is thought to be a site of integration of positively and negatively valenced information and action selection.

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Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards. 48 initially reported that selective bilateral excitotoxic lesions of the nucleus accumbens core region but not the anterior cingulate or the medial PFC resulted in more impulsive choice using a temporal discounting task. In two experiments we induced nucleus accumbens core NAcc dysfunction in rats receiving fear discrimination consisting of cues for danger uncertainty and safety. The nucleus accumbens receives glutaminergic dopaminergic and histaminergic input fibers from different areas of the brain. Cognitive and emotional factors also influence sleepwake behaviour.

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It is present in the inner region of the nucleus accumbens. In general this result has held up in subsequent studies using different variants of the delayed discounting procedure. Nevertheless the circuit mechanisms underlying the diverse functions of the NAc remain poorly understood. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior. NMDAR N-methyl- D -.

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Nucleus accumbens NAc neurons encode features of stimulus learning and action selection associated with rewards. Previous studies suggest that. Rapid discrimination of uncertain threat and safety. The nucleus accumbens core is an important interface between the limbic and motor systems and plays a particularly important role in motivated behavior. NAChR nicotinic acetylcholine recep tor.

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